产品货号：
Z32454
中文名称：
CARD9抗体(N-term)
英文名称：
Anti-CARD9 Antibody(N-term)(Clone#2156CT20.4.85)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CARD9 Antibody (N-term) (Clone#2156CT20.4.85) |
| 指标别名 | CARD9;hCARD9 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | CARD9 |
| 克隆号 | 2156CT20.4.85 |
| 抗体来源 | Mouse |
| 免疫原 | This CARD9 antibody is generated from a mouse immunized with a recombinant protein from human CARD9. |
| 计算分子量 | 62kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Adapter protein that plays a key role in innate immune response to a number of intracellular pathogens,such as C.albicans and L.monocytogenes.Is at the crossroads of ITAM- tyrosine kinase and the Toll-like receptors (TLR) and NOD2 signaling pathways.Probably controls various innate immune response pathways depending on the intracellular pathogen.In response to L.monocytogenes infection,acts by connecting NOD2 recognition of peptidoglycan to downstream activation of MAP kinases (MAPK) without activating NF-kappa-B.Also involved in activation of myeloid cells via classical ITAM-associated receptors and TLR:required for TLR-mediated activation of MAPK,while it is not required for TLR-induced activation of NF-kappa-B (By similarity).Controls CLEC7A (dectin-1)-mediated myeloid cell activation induced by the yeast cell wall component zymosan,leading to cytokine production and innate anti-fungal immunity:acts by regulating BCL10-MALT1-mediated NF-kappa-B activation pathway.Activates NF-kappa-B via BCL10.In response to the hyphal form of C.albicans,mediates CLEC6A (dectin-2)-induced I-kappa-B kinase ubiquitination,leading to NF-kappa-B activation via interaction with BCL10.In response to fungal infection,may be required for the development and subsequent differentiation of interleukin 17-producing T helper (TH-17) cells. |
| Uniprot ID | Q9H257 |
相关搜索：CARD9抗体(N-term)，CARD9单抗，Anti-CARD9 Antibody(N-term)(Clone#2156CT20.4.85)